Recent advances in our knowledge of sleeping sickness

Neglected Disease – African Sleeping Sickness: Recent Synthetic and Modeling Advances

Human African Trypanosomiasis (HAT) also called sleeping sickness is caused by subspecies of the parasitic hemoflagellate Trypanosoma brucei that mostly occurs in sub-Saharan Africa. The current chemotherapy of the human trypanosomiases relies on only six drugs, five of which have been developed more than 30 years ago, have undesirable toxic side effects and most of them show drug-resistance. T...

Recent advances in our knowledge of the Myxozoa.

In the last few years two factors have helped to significantly advance our understanding of the Myxozoa. First, the phenomenal increase in fin fish aquaculture in the 1990s has lead to the increased importance of these parasites; in turn this has lead to intensified research efforts, which have increased knowledge of the development, diagnosis. and pathogenesis of myxozoans. The hallmark discov...

Recent advances in our knowledge of Australian anisakid nematodes

Anisakidosis is an emerging infection associated with a wide range of clinical syndromes in humans caused by members of the family Anisakidae. Anisakid nematodes have a cosmopolitan distribution and infect a wide range of invertebrates and vertebrates during their life cycles. Since the first report of these parasites in humans during the early 60s, anisakid nematodes have attracted considerabl...

Recent Advances in Our Knowledge about Vitamin B1

Sleeping Sickness Wakes Again

Sleeping sickness of horses was, as reeentiy as the IQSO's, the most devastating livestock disease in the United States. Horses died by the hundreds of thousands in the Midwestern United States, in California, and along the Atlantic seaboard at a period which coincided with the beginning of the sharp decline in the use of horses on the farm. Losses were so severe in some areas that the inevitab...